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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
25.15
Human Site:
Y525
Identified Species:
55.33
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
Y525
Q
N
G
K
S
K
G
Y
A
F
I
E
F
A
S
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
T797
S
Y
S
A
T
E
E
T
L
Q
E
V
F
E
K
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
Y753
Q
N
G
K
S
K
G
Y
A
F
I
E
F
A
S
Dog
Lupus familis
XP_850477
699
75739
Y514
Q
N
G
K
S
K
G
Y
A
F
I
E
F
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
Y526
P
H
G
K
P
K
G
Y
A
F
I
E
F
A
S
Rat
Rattus norvegicus
P13383
713
77129
Y528
P
H
G
K
S
K
G
Y
A
F
I
E
F
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
Y468
H
Q
G
R
P
K
G
Y
A
F
V
E
F
S
T
Chicken
Gallus gallus
P15771
694
75622
Y500
N
Q
G
R
P
K
G
Y
A
F
V
E
F
P
T
Frog
Xenopus laevis
P20397
651
70177
F458
K
G
F
A
F
I
E
F
S
S
A
E
D
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
I280
P
S
T
T
G
E
Q
I
Q
E
F
F
E
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
V294
F
A
K
H
G
E
V
V
S
V
R
I
P
T
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
6.6
100
100
N.A.
80
86.6
N.A.
53.3
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
86.6
93.3
N.A.
80
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
0
0
0
0
64
0
10
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
28
19
0
0
10
10
73
10
19
0
% E
% Phe:
10
0
10
0
10
0
0
10
0
64
10
10
73
0
0
% F
% Gly:
0
10
64
0
19
0
64
0
0
0
0
0
0
0
0
% G
% His:
10
19
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
46
10
0
0
0
% I
% Lys:
10
0
10
46
0
64
0
0
0
0
0
0
0
0
19
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
28
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
28
0
0
0
28
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
28
19
0
0
0
0
10
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
0
19
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
10
0
37
0
0
0
19
10
0
0
0
10
46
% S
% Thr:
0
0
10
10
10
0
0
10
0
0
0
0
0
10
19
% T
% Val:
0
0
0
0
0
0
10
10
0
10
19
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _